The Low Surface Brightness Extent of the Fornax Cluster

We have used a large format CCD camera to survey the nearby Fornax cluster and its immediate environment for low luminosity low surface brightness galaxies. Recent observations indicate that these are the most dark matter dominated galaxies known and so they are likely to be a good tracer of the dark matter in clusters. We have identified large numbers of these galaxies consistent with a steep faint end slope of the luminosity function (alpha~ -2) down to MB ~ -12. These galaxies contribute almost the same amount to the total cluster light as the brighter galaxies and they have a spatial extent that is some four times larger. They satisfy two of the important predictions of N-body hierarchical simulations of structure formation using dark halos. The luminosity (mass ?) function is steep and the mass distribution is more extended than that defined by the brighter galaxies. We also find a large concentration of low surface brightness galaxies around the nearby galaxy NGC1291.Comment: 16 pages, 6 figure

Magnetic fields from reionisation

We present a complementary study to a new model for generating magnetic fields of cosmological interest. The driving mechanism is the photoionisation process by photons provided by the first luminous sources. Investigating the transient regime at the onset of inhomogeneous reionisation, we show that magnetic field amplitudes as high as $2 \times 10^{-16}$ Gauss can be obtained within a source lifetime. Photons with energies above the ionisation threshold accelerate electrons, inducing magnetic fields outside the Stroemgren spheres which surround the ionising sources. Thanks to their mean free path, photons with higher energies propagate further and lead to magnetic field generation deeper in the neutral medium. We find that soft X-ray photons could contribute to a significant premagnetisation of the intergalactic medium at a redshift of z=15.Comment: accepted for publication in A&

Enhancing the gain by quantum coherence in terahertz quantum cascade lasers

We propose and study GaAs/AlGaAs terahertz frequency quantum cascade lasers in which mid-infrared radiation is used as a coherent drive for enhancing the terahertz gain

Limits on dust emission from z~5 LBGs and their local environments

We present 1.2mm MAMBO-2 observations of a field which is over-dense in Lyman Break Galaxies (LBGs) at z~5. The field includes seven spectroscopically-confirmed LBGs contained within a narrow (z=4.95+/-0.08) redshift range and an eighth at z=5.2. We do not detect any individual source to a limit of 1.6 mJy/beam (2*rms). When stacking the flux from the positions of all eight galaxies, we obtain a limit to the average 1.2 mm flux of these sources of 0.6mJy/beam. This limit is consistent with FIR imaging in other fields which are over-dense in UV-bright galaxies at z~5. Independently and combined, these limits constrain the FIR luminosity (8-1000 micron) to a typical z~5 LBG of LFIR<~3x10^11 Lsun, implying a dust mass of Mdust<~10^8 Msun (both assuming a grey body at 30K). This LFIR limit is an order of magnitude fainter than the LFIR of lower redshift sub-mm sources (z~1-3). We see no emission from any other sources within the field at the above level. While this is not unexpected given millimetre source counts, the clustered LBGs trace significantly over-dense large scale structure in the field at z = 4.95. The lack of any such detection in either this or the previous work, implies that massive, obscured star-forming galaxies may not always trace the same structures as over-densities of LBGs, at least on the length scale probed here. We briefly discuss the implications of these results for future observations with ALMA.Comment: 10 pages, 6 figures, MNRAS Accepte

Ex vivo normothermic perfusion of isolated segmental porcine bowel: a novel functional model of the small intestine.

BACKGROUND: There is an unmet need for suitable ex vivo large animal models in experimental gastroenterology and intestinal transplantation. This study details a reliable and effective technique for ex vivo normothermic perfusion (EVNP) of segmental porcine small intestine. METHODS: Segments of small intestine, 1.5-3.0 m in length, were retrieved from terminally anaesthetized pigs. After a period of cold ischaemia, EVNP was performed for 2 h at 37°C with a mean pressure of 80 mmHg using oxygenated autologous blood diluted with Ringer's solution. The duration of EVNP was extended to 4 h for a second set of experiments in which two segments of proximal to mid-ileum (1.5-3.0 m) were retrieved from each animal and reperfused with whole blood (control) or leucocyte-depleted blood to examine the impact of leucocyte depletion on reperfusion injury. RESULTS: After a mean cold ischaemia time of 5 h and 20 min, EVNP was performed in an initial group of four pigs. In the second set of experiments, five pigs were used in each group. In all experiments bowel segments were well perfused and exhibited peristalsis during EVNP. Venous glucose levels significantly increased following luminal glucose stimulation (mean(s.e.m.) basal level 1.8(0.6) mmol/l versus peak 15.5(5.8) mmol/l; P < 0.001) and glucagon-like peptide 1 (GLP-1) levels increased in all experiments, demonstrating intact absorptive and secretory intestinal functions. There were no significant differences between control and leucocyte-depleted animals regarding blood flow, venous glucose, GLP-1 levels or histopathology at the end of 4 h of EVNP. CONCLUSIONS: This novel model is suitable for the investigation of gastrointestinal physiology, pathology and ischaemia reperfusion injury, along with evaluation of potential therapeutic interventions

Whole-exome sequencing gives additional benefits compared to candidate gene sequencing in the molecular diagnosis of children with growth hormone or IGF-1 insensitivity

Ipsen UK!(HLS). Sandoz Pharmaceutical

Galaxy Formation in Preheated Intergalactic Media

We outline a scenario of galaxy formation in which the gas in galaxy-forming regions was preheated to high entropy by vigorous energy feedback associated with the formation of stars in old ellipticals and bulges and with AGN activity. Such preheating likely occurred at redshifts z ~ 2-3, and can produce the entropy excess observed today in low-mass clusters of galaxies without destroying the bulk of the Lyman alpha forest. Subsequent galaxy formation is affected by the preheating, because the gas no longer follows the dark matter on galaxy scales. The hot gas around galaxy haloes has very shallow profiles and emits only weakly in the X-ray. Cooling in a preheated halo is not inside-out, because the cooling efficiency does not change significantly with radius. Only part of the gas in a protogalaxy region can cool and be accreted into the final galaxy halo. The accreted gas is likely in diffuse clouds and so does not lose angular momentum to the dark matter. Cluster ellipticals are produced by mergers of stellar systems formed prior to the preheating, while large galaxy disks form in low-density environments where gas accretion can continue to the present time.Comment: 11 pages, 7 figures, MNRAS submitte

Simulation of radiation driven wind from disc galaxies

We present 2-D hydrodynamic simulation of rotating galactic winds driven by radiation. We study the structure and dynamics of the cool and/or warm component($T \simeq 10^4$ K) which is mixed with dust. We have taken into account the total gravity of a galactic system that consists of a disc, a bulge and a dark matter halo. We find that the combined effect of gravity and radiation pressure from a realistic disc drives the gas away to a distance of $\sim 5$ kpc in $\sim 37$ Myr for typical galactic parameters. The outflow speed increases rapidly with the disc Eddington parameter $\Gamma_0(=\kappa I/(2 c G \Sigma)$) for $\Gamma_0 \ge 1.5$. We find that the rotation speed of the outflowing gas is $\lesssim 100$ km s$^{-1}$. The wind is confined in a cone which mostly consist of low angular momentum gas lifted from the central region.Comment: 10 pages, 11 figures, Accepted for publication in MNRA

Probing Hot Gas in Galaxy Groups through the Sunyaev-Zeldovich Effect

We investigate the potential of exploiting the Sunyaev-Zeldovich effect (SZE) to study the properties of hot gas in galaxy groups. It is shown that, with upcoming SZE surveys, one can stack SZE maps around galaxy groups of similar halo masses selected from large galaxy redshift surveys to study the hot gas in halos represented by galaxy groups. We use various models for the hot halo gas to study how the expected SZE signals are affected by gas fraction, equation of state, halo concentration, and cosmology. Comparing the model predictions with the sensitivities expected from the SPT, ACT and Planck surveys shows that a SPT-like survey can provide stringent constraints on the hot gas properties for halos with masses M ~> 10^{13} h^{-1}Msun. We also explore the idea of using the cross correlation between hot gas and galaxies of different luminosity to probe the hot gas in dark matter halos without identifying galaxy groups to represent dark halos. Our results show that, with a galaxy survey as large as the Sloan Digital Sky Survey and with the help of the conditional luminosity function (CLF) model, one can obtain stringent constraints on the hot gas properties in halos with masses down to 10^{13} h^{-1}Msun. Thus, the upcoming SZE surveys should provide a very promising avenue to probe the hot gas in relatively low-mass halos where the majority of L*-galaxies reside.Comment: 22 pages, 16 figures, accepted for publication on MNRA

Galaxy morphology and evolution from SWAN Adaptive Optics imaging

We present the results from adaptive optics (AO) assisted imaging in the Ks band of an area of 15 arcmin^2 for SWAN (Survey of a Wide Area with NACO). We derive the high resolution near-IR morphology of ~400 galaxies up to Ks~23.5 in the first 21 SWAN fields around bright guide stars, carefully taking into account the survey selection effects and using an accurate treatment of the anisoplanatic AO PSF. The detected galaxies are sorted into two morphological classes according to their Sersic index. The extracted morphological properties and number counts of the galaxies are compared with the predictions of different galaxy formation and evolution models, both for the whole galaxy population and separately for late-type and early-type galaxies. This is one of the first times such a comparison has been done in the near-IR, as AO observations and accurate PSF modeling are needed to obtain reliable morphological classification of faint field galaxies at these wavelengths. For early-type galaxies we find that a pure luminosity evolution model, without evidence for relevant number and size evolution, better reproduces the observed properties of our Ks-selected sample than current semi-analytic models based on the hierarchical picture of galaxy formation. In particular, we find that the observed flattening of elliptical galaxy counts at Ks~20 is quantitatively in good agreement with the prediction of the pure luminosity evolution model that was calculated prior to the observation. For late-type galaxies, while both models are able to reproduce the number counts, we find some hints of a possible size growth. These results demonstrate the unique power of AO observations to derive high resolution details of faint galaxies' morphology in the near-IR and drive studies of galaxy evolution.Comment: 15 pages, 10 figures. A&A, in press. Final version with corrected typo